A lot has already happened during the 2022-23 English Premier League season. Indeed, the overall power structure is mostly as intended, but there are a bunch of surprises with which the public is still grappling. Our latest batch of English Premier League picks will seek to answer perhaps the biggest question to emerge so far: Is Manchester City still the team to beat, or has Arsenal officially usurped them?
Quickly pillaging through the most popular markets for online soccer betting will show oddsmakers aren't ready to give the edge to Arsenal. In fact, the overwhelming majority of betting odds for the Premier League still favor Manchester City by a wide margin over the field. But this may no longer be the correct call.
We'll expand on our thoughts in a moment. But first, let's have a look at the latest English Premier League betting odds for all of the action taking place on October 1 and October 2. Please note that all of these odds on the English Premier League come from Bovada and are accurate entering Thursday, September 22:
| Match Date | Favorite |  | | | Underdog |
|---|---|---|---|---|---|
| 10/1/22 | Arsenal | +110 | +250 (Draw) | +240 | Tottenham |
| 10/1/22 | Newcastle | +125 | +240 (Draw) | +220 | Fulham |
| 10/1/22 | Brentford | +110 | +240 (Draw) | +250 | Bournemouth |
| 10/1/22 | Liverpool | -320 | +440 (Draw) | +900 | Brighton |
| 10/1/22 | Southampton | +115 | +240 (Draw) | +230 | Everton |
| 10/1/22 | Chelsea | -115 | +250 (Draw) | +330 | Crystal Palace |
| 10/1/22 | West Ham | -110 | +250 (Draw) | +300 | Wolves |
| 10/1/22 | Manchester City | -310 | +460 (Draw) | +750 | Manchester United |
| 10/2/22 | Leeds | +160 | +250 (Draw) | +165 | Aston Villa |
| 10/2/22 | Leicester | -125 | +290 (Draw) | +320 | Nottenham Forest |
Like always, be sure to double-check these soccer betting lines prior to making your English Premier League picks. Single-match odds don't tend to shift all that much, but when many of the "favorites" are paying out better than even money, you can definitely expect a bunch of changes right up until the opening whistle.
In the meantime, if you haven't yet found a place to bet on the English Premier League, you should make it a point to check out our reviews of the top online sportsbooks. All the information we've provided is specially designed to help you find the best English Premier League betting sites in 2022.
Finally, while we're most interested in tackling the sudden rivalry between Arsenal and Manchester City, that's not all we'll cover. After going through their respective matches, we've also got other English Premier League picks that fall under our "best bets" umbrella. Let's get to it!
Arsenal is Now the EPL Team to Beat
Skeptics point to Arsenal's goal differential when trying to paint them as vulnerable. They have outscored opponents by 10 goals, compared to 11 from Tottenham and a whopping 17 from Manchester City.
Still, this doesn't even tell part of the story.
Arsenal has hit on a ton of young talent while getting relatively good health from Saka, Gabriel Martinelli, Emile Smith-Rowe and Fabio Vieira. Their defense under Mikel Arteta has also made strides.
What's happening right now isn't a fluke. It's a club coming into their own at both ends of the pitch, and they should have no trouble dispatching the slumping offense of Tottenham.
OSB Prediction: Arsenal (+110)
Manchester City Should Still Be a Staple in Your English Premier League Picks
While we might think that Arsenal has become the team to beat in the EPL, these English Premier League picks would be remiss if they didn't acknowledge that Manchester City was yet again their own dynamo.
Never mind that they have a viable shot at a three-peat. This is a dominant team, on both sides of the ball, that somehow managed to add Norwegian Erling Haaland to the fold. That is categorically unfair.
Indeed, there are matches in which Manchester City looks unbeatable. We expect to see one of those outings against the rival—and struggling—Manchester United.
OSB Prediction: Manchester City (-310)
Expect Liverpool to Make Extremely Quick Work of Brighton
Liverpool has no doubt disappointed relative to lofty expectations. Many had them pegged as the EPL's second best team, but they currently sit under .500, at 2-3-1.
Facing off against Brighton should prove to be a natural remedy. Their defense is among the league's best, but they don't have much of an offensive attack of which to speak. Liverpool, meanwhile, could be 5-0-1 when you go back and watch the endings from three of their matches.
Granted, we'll allow for some doubt to creep in here. Brighton's defense on the frontline has been that aggressive and effective. Overall, though, we trust Liverpool to start closing their matches on higher notes.
OSB Prediction: Liverpool (-320)
Newcastle is on Upset Alert Against Fulham...Plan Your English Premier League Picks Accordingly
Oddsmakers in this matchup are treating Fulham like they're playing as poorly as preseason projections anticipated. That doesn't sit right with us.
Fulham has indeed struggled to cobble together wire-to-wire victories. Their 11 goals allowed is among the highest for any team over .500. But the high-octane scoring clout of Aleksandar Mitrovic continues to buoy one of the scariest offenses in the EPL.
Newcastle, meanwhile, has looked stagnant and often lifeless when attempting to generate shots on goal. Their ball movement is inconsistent, and right now, they don't have anyone who can be counted on to reliably create from a standstill or on the break. This feels like a great opportunity to more than double up on your investment.
OSB Prediction: Fulham (+220)
Chelsea Should be Able to Cruise Past Crystal Palace
Chelsea's offense has underperformed to a detriment thus far. As of now, they have scored fewer goals (eight) than they have allowed (nine). It's a minor miracle that they've been able to nab three victories through their first six matches.
Most don't think the stagnancy on offense will continue. Even if it does, the defense has been stifling—and is built to remain that way.
Beating a lower-level team like Crystal Palace is almost a given. But if Chelsea can start moving the ball better in wide-open spaces, they'll be more than just the occasional single-match bet moving forward.
OSB Prediction: Chelsea (-115)
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