Best 2022 NFL Prop Bets in Week 14 Include Christian McCaffrey, Kyler Murray, Tyreek Hill

As we journey later into the 2022 NFL regular season, it's important to get more creative with your wagers. Single-game investments are still great. But with the playoff field starting to take shape, the scope of games worth pouncing on becomes noticeably smaller. But that's not a problem. Because that just means you can lean into weekly 2022 NFL prop bets to fatten up your football portfolio.

For Week 14 in particular, the field is loaded with online NFL prop betting options. From Christian McCaffrey's total yards in the absence of Jimmy Garoppolo to quarterback rushing to wide receiver performances, we've cobbled together a treasure trove of Week 14 NFL prop predictions that pay out 10-to-1 or better! Here are our favorite picks and the latest odds on them, courtesy of the folks over at Bovada:

Event
Christian McCaffrey 100+ Scrimmage Yards and 1+ Receiving TDs	+1000
Both Kyler Murray and Daniel Jones to each Record 50+ Rushing Yards	+1200
All of Davante Adams	Tyreek Hill and DK Metcalf to each Record 100+ Receiving Yards

Please remember to double-check these NFL online betting odds right up until you place your wager. Football betting lines are always subject to change through opening kickoff, and NFL prop bets can be especially turbulent. For reference, our NFL prop betting odds are accurate entering Wednesday, December 7. All the picks we're making will unfold over the course of Sunday, December 11. That gives the linemakers plenty of time to make adjustments.

In order to stay on top of any changes to the latest online NFL betting odds, it's important to find the perfect sportsbook. That's where our reviews of the top online sportsbooks come in. We provide you with all the tools you need to find the best NFL online betting sites in 2022.

Ready to bet on some 2022 NFL props? Good. Because so are we.

Christian McCaffrey is Our Favorite Week 14 NFL Prop Bet...And It's Not Even Close

The Bet: Christian McCaffrey will finish Week 14 with 100+ Scrimmage Yards and 1+ Receiving Touchdowns (+1000).

Christian McCaffrey's performance has been up and down since he arrived in San Francisco, coming over in a mega-trade with the Carolina Panthers. He has turned in weeks where he easily clears 100 yards from scrimmage and other where he fails to reach that plateau.

This shouldn't be an issue against the Tampa Bay Buccaneers on Sunday. The Niners will be without starting quarterback Jimmy Garoppolo and instead starting rookie Brock Purdy. The odds of them trusting Purdy to throw a ton of passes are slim. That should mean more volume for McCaffrey on the ground. This might even mark his first 20-carry day since joining the Niners.

Some analysts have expressed concern San Francisco might just allocate more touches to fellow running back Jordan Love. That's not the end of the world. McCaffrey will still factor prominently into the offense and always has his pass-catching volume to prop up his yards from scrimmage.

Perhaps most importantly, while the Bucs defense ranks fifth in points allowed per game, they have struggled to stop the run across the middle of the field. This should be an easy 100-plus-yard, one-or-more-touchdown outing from McCaffrey.

Christian McCaffrey To finish with 100+ yards and 1+ touchdowns

+1000

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Kyle Murray and Daniel Jones Combine for an Interesting 2022 NFL Prop Bet

The Bet: Both Kyler Murray and Daniel Jones will each record 50+ Rushing Yards (+1200)

Investing in this 2022 NFL prop bet is risky. But that's why it pays out 12-to-1. And frankly, we love it.

Both Kyler Murray (facing the New England Patriots) and Daniel Jones (going up against the Philadelphia Eagles) are squaring off opposite top-tier defenses. But we still expect each to eclipse the 50-yard rushing mark.

Not only has this been a regular occurrence for both, but their offenses desperately need the output. Murray doesn't have a ton of weapons around him; his legs might be the Arizona Cardinals' most efficient offensive option at this point. Jones, meanwhile, has become a scrambling machine—in no small part because he's clearly not confident in his arm strength and also isn't surrounded by a ton of talent at wide receiver. Plus, for as dominant as Philadelphia's defense has been, they rank 24th in net yards allowed per rushing attempt and have struggled, at times, to contain quarterbacks when they roll out.

If we had to pick a weak point on this bet, it'd actually be Murray. He's the more talented passer, so there's a chance the play-calling for Arizona skews towards protecting him against New England's rush. Overall, though, we're pretty confident both he and Jones clear the 50-yard rushing mark.

Kyler Murray and Daniel Jones To finish with 50+ rushing yards

+1200

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Bet on Davante Adams, DK Metcalf and Tyreek Hill to Rack Up Reception Yards

The Bet: All of Davante Adams, Tyreek Hill and DK Metcalf will each record 100+ Receiving Yards (+2000).

Let's tackle these in order.

Davante Adams' 100-yard yard day feels like a given to us. The Los Angeles Rams have completely fallen apart following last year's Super Bowl victory, and they have a tougher time shutting down star wideouts than usual.

Tyreek Hill seems like a similarly sized certainty. His Miami Dolphins love to chase long-yardage plays, and they're facing a Los Angeles Chargers secondary that isn't athletic enough to keep up with his downfield speed.

DK Metcalf is more of a coin toss. But that may just be because we don't totally trust Seattle Seahawks quarterback Geno Smith to find him. This isn't necessarily rational. Geno Smith has thrown the ball like a top-12 quarterback this year, and it shows. And with the Seahawks facing a rather inviting Panthers defense, Metcalf and the entire Seattle offense should be in for a huge performance on Sunday.

Davante Adams, Tyreek Hill and DK Metcalf To finish with 100+ receiving yards

+1000

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Take a look at this list of the top online sportsbooks so you can decide which one to use for all of your 2022 NFL betting: