Pistons to pound Celtics for 8th straight victory on Wednesday

What: NBA Picks
Who: Boston Celtics at Detroit Pistons
When: Wednesday, February 26, 7:00 p.m.

After cruising to a 111-101 victory over the Toronto Raptors on Tuesday night, the Celtics are in Detroit for the second of their back-to-back road games. While Boston is on a six-game winning streak, the Pistons have won seven in a row to surge up the Eastern Conference standings.

Let's look at the latest betting lines for the game. Odds are subject to change.

	Spread	Money Line	Total Points
Boston Celtics	-4.5 (-110)	-175	Un 225.5 (110)
Detroit Pistons	+4.5 (-110)	+150	Ov 225.5 (-110)

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Pistons vs Celtics Betting Trends

Detroit is a 4.5-point home underdog at Little Caesars Arena, where they are 15-13 this season with a 13-14-1 record against the spread. However, they're 9-6-1 ATS as a home underdog. Winners of seven straight, the Pistons sit in 6th-place in the East with a 32-26 overall record, just one game back of both the Bucks and the Pacers. J.B. Bickerstaff club is 22-20 against teams in their own conference.

Boston's 24 road victories are the most in the NBA, but they're only 13-12-1 ATS as an away favorite. Winners of six in a row, the Celtics have the third-best record (42-16) in the entire league. Joe Mazzulla's team is 30-9 against conference opponents.

The over/under for Wednesday's game is set at 225.5 points. The UNDER is 18-11 in Celtics road contests and 14-14 in Detroit home games.

Cade Cunningham drops 30+ PTS for the second night in a row to lead the @DetroitPistons to their 7th straight win!

🔥 32 PTS
🔥 9 REB
🔥 7 AST
🔥 3 STL

This ties Detroit's longest winning streak since the 2014-15 season. pic.twitter.com/vfSUHdWA09

— NBA (@NBA) February 25, 2025

Cade's coming of age

Cade Cunningham led the Pistons to a 106-97 victory over the Clippers on Monday night, finishing with 32 points, nine rebounds, seven assists and three steals. Detroit has won 21 of its last 30 games, and is on its first seven-game winning streak in 10 years.

After earning his first All-Star berth, Cunningham is beginning to look like a lock for All-NBA. The 23-year-old point guard is the only player other than Nikola Jokic to average at least 25 points, nine assists and six rebounds this season.

Tatum in fine form

Jayson Tatum ranks seventh in the NBA in scoring at 26.8 points per game. Jaylen Brown has been almost as good, averaging 20.8 points, 6.8 rebounds, 5.0 assists and 1.0 steals per game since the start of 2025.

Winners of five straight, the reigning champions look to be locked into the No. 2 seed in the East, with the Cavaliers holding a healthy lead in the standings.

I sat down with Jayson Tatum & asked him about being overlooked in the next "face of the NBA" discussion. It led to a riveting conversation on respect, winning & what matters to him: “I don’t really want to insert myself in things that can be debated.” https://t.co/IJHAdgHiaO

— Michael Lee (@MrMichaelLee) February 25, 2025

Detroit Pistons vs Boston Celtics NBA Picks

Two of the NBA's hottest teams square off on Wednesday night with long, multi-game win streaks on the line. The Celtics have claimed all three matchups with Detroit this season - a 123-99 victory on Dec. 12, a 130-120 win on Dec. 4, and a 124-118 W on Oct. 26.

But, Boston is playing the second of back-to-back matchups on the road and the red-hot Pistons should be plenty motivated to avoid the season-series sweep. We'll take Detroit to cover (4.5) at home and win outright (+150) with the UNDER (223).

Detroit Pistons To win vs Boston Celtics